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Singapore Clinical Trial: A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)

Singapore, Aug. 11 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy ... Read More


Clinical Trial: Immunoglobulin Replacement Therapy (IgRT) Versus Antibiotic Prophylaxis (PA) in Patients Treated by CD19-targeted Chimeric Antigen Receptor (CAR)T Cells for a B Cell Acute Lymphoblastic Leukemia or a B Cell Lymphoma

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07754682) titled 'Immunoglobulin Replacement Therapy (IgRT) Versus Antibiotic Prophylaxis (PA) in Patients Tr... Read More


Clinical Trial: Radscopal Radiotherapy Plus Immunotherapy for Chemotherapy-Ineligible Patients With Newly Diagnosed Metastatic Nasopharyngeal Cancer: A Single-Center, Open-Label, Phase II Study

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07756190) titled 'Radscopal Radiotherapy Plus Immunotherapy for Chemotherapy-Ineligible Patients With Newly D... Read More


Singapore Clinical Trial: A Phase III, 52-week, prospective, randomized, double-blind, placebo-controlled, parallel-group, multi-center study, with a primary efficacy endpoint at 12 weeks, to determine the efficacy, safety, and tolerability of fixed doses of 15 mg bid and 30 mg bid of evenamide as add-on in patients with documented treatment-resistant schizophrenia, which is not adequately controlled by a stable therapeutic dose of the patient’s current antipsychotic medication(s).

Singapore, Aug. 11 -- The Health Sciences Authority received information related to the study titled 'A Phase III, 52-week, prospective, randomized, double-blind, placebo-controlled, parallel-group, m... Read More


Singapore Clinical Trial: A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer

Singapore, Aug. 11 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab... Read More


Clinical Trial: Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07756554) titled 'Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admissi... Read More


Clinical Trial: Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in Elderly Patients With Chemotherapy

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07756073) titled 'Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in E... Read More


Clinical Trial: Gilteritinib-Azacitidine-Venetoclax Combination Therapy in Patients With Relapsed/Refractory Leukemia

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07755202) titled 'Gilteritinib-Azacitidine-Venetoclax Combination Therapy in Patients With Relapsed/Refractor... Read More


Clinical Trial: Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07755761) titled 'Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlle... Read More


Clinical Trial: Suboccipital Release vs Smartphone App Guided Exercises in Smartphone Neck Syndrome

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07756125) titled 'Suboccipital Release vs Smartphone App Guided Exercises in Smartphone Neck Syndrome' on Aug... Read More